Two-Dimensional Correlation Spectroscopy
Dr. Isao Noda, Procter & Gamble Company, West Chester, OH
COURSE DESCRIPTION
Two-dimensional (2D) correlation spectroscopy is a relatively new addition to the field of optical spectroscopy. In 2D spectroscopy, a
spectrum is obtained as a function of two independent spectral valuables, such as wavenumbers. Peaks are spread over the second
dimension, thereby simplifying the visualization of complex spectra consisting of many overlapped bands, and thus enhancing spectral
resolution. Relationships among various spectral bands are characterized by the presence or absence of 2D cross peaks. The new correlation
formalism provides a unified model-free path to the construction of useful 2D correlation spectra for wide ranges of spectral data, obtained by
common electromagnetic probes (e.g., IR, Raman, NIR, UV, visible, fluorescence, x-ray, NMR, and so on) under various experimental conditions.
In fact, this technique can also be extended to the analysis of data outside of spectroscopy, such as chromatography and microscopy. In this
short course, an overview and detailed tutorial will be provided for this powerful and versatile technique with many application examples,
including the study of synthetic polymers, bio-molecules, surfaces, and many other industrially important systems. The course includes the
hands-on exercise of actual 2D correlation analysis by using free software.
WHO SHOULD ATTEND
The course is intended for general audience with some basic technical background, including chemists, physicists, biologists, engineers, material
scientists, and students at graduate or undergraduate level. Almost anyone who uses spectroscopic techniques in a part of their work will benefit
from taking this course. Some basic mathematical tools, such as Fourier transform and correlation analysis, are used as a background, but no
in-depth knowledge in mathematics is required.
TOPICS
Part 1. Basics
• Introduction to 2D correlation spectroscopy
• Background information to be a 2D spectroscopist
• How to get started with 2D spectroscopy
• Properties and interpretation of 2D correlation spectra
• Computation and construction of 2D spectra
Part 2. Case studies of application examples
• Phenomena studied include: chemical reactions, rheology
and mechanical deformation, thermal effect such as melting
and crystallization, electrochemistry, pressure induced
effects, etc.
• Analytical probes used include: IR, NIR, Raman,
fluorescence, NMR, and even chromatography.
• Systems analyzed include: synthetic and natural polymers,
biomolecules, colloids and solutions, and many more.
Part 3. Advanced topics (optional)
• Fundamental theory of 2D correlation analysis
• New developments in 2D spectroscopy
Part 4. Software hands-on tutorial
• Demonstration of free 2D software
RECOMMENDED TEXT
Although not an absolute requirement, the participant is strongly encouraged to obtain the textbook on the topic prior to attending the
course.
I. Noda and Y. Ozaki, Two-Dimensional Correlation Spectroscopy — Applications in Vibrational and Optical Spectroscopy, Wiley:
Chichester, UK, 2004.
ABOUT THE INSTRUCTOR
Dr. Isao Noda was born in Tokyo, Japan. He came to the United States in 1969 and was graduated from Columbia University
in the City of New York in 1974 with B.S. degree in chemical engineering. He also received his M.S. in bioengineering (1976), as
well as M.Phil. (1978) and Ph.D. (1979) in chemical engineering from Columbia. In 1997 he received D.Sc. degree in chemistry
from the University of Tokyo. He is currently a Research Fellow of the Procter and Gamble Company in Cincinnati, Ohio. His
research interest is in the broad area of polymer science and spectroscopy. He is well known for the development of two-dimensional
infrared (2D IR) correlation spectroscopy. He has also been actively involved in the research and development of a novel class of
bio-based biodegradable plastics called NodaxTM. He is a recipient of the 1991 William F. Meggers Award from the Society for
Applied Spectroscopy and the 2002 Williams-Wright Award from the Coblentz Society. In 2002, he was appointed to the position
of Honorary Adjunct Professor of the Department of Biological Science and Biotechnology at Tsinghua University in Beijing, China.
He was selected as the 2005 Chemist of the Year by the Cincinnati Section of the American Chemical Society. He received the
International Academic Cooperation and Exchange Medal in 2008 from the Chinese Chemical Society and Chinese Optical Society.
Dr. Noda is the recipient of the 2009 New York Section of the Society for Applied Spectroscopy Gold Medal Award which will be
presented at this year’s EAS.
